What is Asthma ?
Asthma is a lower respiratory tract pulmonary obstructive disease which is also called as "Reactive Airway Disease".
Definition :
Asthma is the chronic inflammatory disease of the airways characterized by variable & recurring symptoms & bronchospasm.
Pathophysiology :
Allergens are responsible for obstruction of airways by either inflammation of airway lining or constriction of bronchial smooth muscles due to activation of mast cells & histamine in immune system charecterized by mucus secretion & episodes of bronchospasm.
Etiology & risk factors :
- Heridatory
- Environemntal triggers
- Allergens
- Air pollution
- Upper respiratory tract infections
- Occupational factors Psychological factors
- Idiopathic
Types :
- Extrinsic asthma : Also called as Atopic asthma caused by allergens such as pollens, animal dander, dust. Often accompanied by allergic rhinitis O eczema & is usually heridatory.
- Intrinsic Asthma : Also known as non- atopic, caused by non allergic factors such as respiratory tract infections, exposure to cold air, changes in air humidity or respiratory irritants.
Sign & Symptoms :
- Wheezing
- Shortness of breath
- Dyspnea
- Tachypnea = RR> 20 breaths/min
- Chest tightness
- Cough
- Tachycardia HR> 100 beats/min
- Hypoxia
- Cyanosis
- Anxiety
Medical & Nursing Management:
- Short acting beta adrenergic blockers for bronchodilation : Terbutaline, Albuterol, Levalbuterol
- Long acting beta adrenergic blockers for bronchodilation : Salmetrol, Formetrol
- Leukotrin modulators to reduce inflammatory response in lungs & to reduce exacerbations : Zafirlukast, Montelukast
- Anticholinergic Drugs
- Ipatropium inhaler or Tiotropium HandiHaler
- Antacids, PPIs : ranitidine, pantoprazole
- Mast cell stabilizers : Cromolyn, Nedocromil
- Steroids : Hydrocortisone, Methylprednisolone IV
- Omalizumab subcutaneously
- Fowler's position to patient
- Explain patient about use of inhaler
- Encourage deep breathing & coughing exercise
- Vital signs to be monitored
- Avoid exposure of allergens
- Nebulization
Distinctive facts :
- Ix- ABG analysis, CXR, PFT, CBC, Sputum analysis
- "Silent chest " important feature of asthma.
- Metered dose inhalers in combination with asthma spacer & dry powder inhaler
- Complications include : Status Asthmaticus
Prognosis :
- Avoiding triggers reduces the level of incidence.
- Proper use of inhalers can improve the prognosis
- Patient who do not use medications properly may die during asthma attack
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